What version of Go are you using (go version)?

$ go version
go version devel go1.18-cf51fb5d68 Sun Oct 17 04:27:13 2021 +0000 darwin/arm64

Does this issue reproduce with the latest release?

No

What operating system and processor architecture are you using (go env)?

$ go env

What did you do?

$ cat main.go
package main

import (
	"fmt"
)

func main() {
	fmt.Println("Hello, playground")
}
$ go run -gcflags=all=-clobberdeadreg main.go

What did you expect to see?

Run ok.

What did you see instead?

Run failed:

$ go run -gcflags=all=-clobberdeadreg main.go
signal: bus error

This starts failing since https://go-review.googlesource.com/c/go/+/350145

And also it does not cause trybot failed, because it seems that we don't have longtest builder for darwin/arm64.

cc @cherrymui @mdempsky